-  The Warrior Within (2024) – Writer, Producer, Director & Editor; An independent documentary on the immunotherapy revolution.

-  Stopping the Next Pandemic (2023), Researcher & Writer; Developed the shooting script for a feature documentary investigating the threat of future pandemics (Best Environmental Film, Cannes World Film Festival). Georama TV Productions & ARTE France.

-  The Cannabis Question (2021) – Writer, Producer, Director & Editor; An examination of the scientific evidence for cannabis's medical uses, potential benefits, and risks. NOVA/PBS.

-  Decoding COVID-19 (2020) – Writer, Producer & Director; A documentary following the race to understand and stop the virus driving the COVID-19 pandemic (Alfred I. duPont–Columbia Award). NOVA/PBS.

-  The Truth About Fat (2020) – Writer, Producer, Director & Editor; A film exploring how body fat is shaped as much by biology as by personal choices. NOVA/PBS.

-  ADDICTION (2018) – Writer, Producer, Director & Editor; A film investigating how drugs alter the brain and why addiction is a chronic, treatable condition rather than a moral failing. NOVA/PBS.

-  Day the Dinosaurs Died (2017) – Writer, Producer, Director & Editor; A film exploring how a seven-mile-wide asteroid triggered a global cataclysm and mass extinction. NOVA/PBS.

-  The Origami Revolution (2017) – Writer, Producer, Director & Editor; The story of how scientists and engineers are harnessing the power of folding to transform technology and design. NOVA/PBS.

-  Can Alzheimer's Be Stopped? (2016) – Writer, Producer, Director & Editor; A film following the race to unravel the causes of Alzheimer's disease and develop treatments to slow or prevent it. Tangled Bank Studios and NOVA/PBS.

- Mass Extinction: Life at the Brink (2014) – Writer, Producer, Director & Editor; A film exploring what Earth’s past mass extinctions can teach us about the threats facing life today. The Smithsonian Channel &Tangled Bank Studios.

-  Cracking Your Genetic Code (2012) – Writer, Producer, Director & Editor; A film exploring the promise and ethical dilemmas of a new era of personalized, gene-based medicine (AAAS Kavli Science Journalism Award). NOVA/PBS.

-  Long Distance Warrior (2010) – Writer, Producer, Director & Editor; A one-hour biography of William McGowan and his battle to break up AT&T’s telecommunications monopoly. PBS.

- What Darwin Never Knew (2009) – Producer; A two-hour special exploring the hidden genetic mechanisms of evolution that Charles Darwin could not explain during his lifetime. NOVA/PBS.

- Rx for Survival: A Global Health Challenge (2005) – Writer, Producer, Director & Editor of Rise of the Superbugs, part of a six-hour series exploring the history of public health and the ongoing global struggle against infectious diseases (Emmy Award). PBS.

-  Shackleton's Voyage of Endurance (2002) – Producer, Writer & Editor; A two-hour special chronicling Ernest Shackleton’s legendary attempt to cross Antarctica (Emmy Award). NOVA/PBS.

-  18 Ways to Make a Baby (2001) – Producer, Director, Writer & Editor; A documentary on the history and development of in vitro fertilization (IVF) and the ethical questions raised by emerging reproductive technologies (AAAS Kavli Science Journalism Award). NOVA/PBS.

- Trillion Dollar Bet (2000) – Writer, Producer & Editor; The story of a mathematical formula that revolutionized modern finance and helped create a multitrillion-dollar industry. NOVA/PBS.

- The Rockefellers (2000) – Editor; A two-hour special chronicling John D. Rockefeller’s ruthless rise to become the world’s first billionaire through the Standard Oil monopoly, and subsequent generations’ quest for redemption. American Experience/PBS.

- MacArthur (2000) – Director, Co-Producer & Editor; A four-hour biography of General Douglas MacArthur. (Emmy Award). American Experience/PBS.

- Science Odyssey (1998) – Co-Producer & Editor of Matters of Life and Death, the second episode of a six-part series exploring a century of scientific discovery. PBS.

-  The Richest Man in the World (1997) – Editor; A two-hour biography of industrialist Andrew Carnegie. American Experience/PBS.

-  Ike (1993) – Editor, Part One; A two-hour biography of President Dwight D. Eisenhower. American Experience/PBS.

-  Nixon: (1990) – Editor, Part Two; A three-hour biography of Richard Nixon. American Experience/PBS.

 
NOVA ScienceNow (2007–2011)
Writer, Producer, Director & Editor of individual segments for the PBS science series.

  • How Does the Brain Work? – Artificial Intelligence
  • Can We Live Forever? – Body Parts
  • Can We Make It to Mars? – Space Dangers; Space Food
  • How Memory Works – (AAAS Kavli Science Journalism Award)
  • The Anthrax Investigation
  • Epigenetics

Hosted by Neil deGrasse Tyson. NOVA/PBS.

 

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  • LD Harrar, Executive Producer of World in the Balance, NOVA, PBS

    "…one of the best and most versatile documentary film producers in the country"

  • Austin Hoyt, Executive Producer, WGBH-TV/PBS

    "Sarah Holt is that rare combination of a thorough and thoughtful journalist, and an artist… I was immediately struck by her ability to tell a story with images and to blend narrative with fact as if it was always meant to be."

  • REVIEW by Peter Keough, The Boston Globe, September 23, 2021

    [In reference to The Cannabis Question]

    "Holt investigates what has been learned about cannabis’s potential risks and medicinal benefits and how its legalization in 30 states after 80 years of prohibition has resulted in confusion and haphazard regulation."

  • Jim Kim, Partners in Health

    "Sarah Holt has a particularly fine ability to see the whole piece, to uncover the compelling picture frame and to present a human story."

  • LD Harrar, Executive Producer of World in the Balance, NOVA, PBS

    "…one of the best and most versatile documentary film producers in the country"

  • Austin Hoyt, Executive Producer, WGBH-TV/PBS

    "[Sarah] has an exquisite visual eye as well as a special gift to frame a story intellectually without draining it of emotion."

  • Jim Kim, Partners in Health

    "[Sarah] knew what she needed to make a great film, and she got it, time after time, sometimes overcoming huge obstacles."